Advance of the cytoskeleton ( Cytoskeleton ) research and liver disease science .

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The cytoskeleton and disease.

Cytoskeletal research in recent years has revolutionized cell biology and biomedicine. The cytoskeleton spans the cytoplasm and interconnects the cell nucleus with the extracellular matrix, thereby forming a structural link between molecules involved in cell communication on the one hand, and gene expression on the other. Since the cytoskeleton is involved in virtually all cellular processes, a...

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Oligodendrocytes have a high rate of synthetic activity and produce vast amounts of myelin. The membrane production requires specific sorting and transport processes and structural support. In culture, oligodendrocytes extend flat membranous sheets containing an extensive cytoskeletal network of microtubules (MTs) and microfilaments (MFs). The microtubules participate in the elaboration and sta...

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Cryoelectron Tomography: Implications for Actin Cytoskeleton Research*

Disclosing undistorted spatial organization of the actin cytoskeleton with molecular resolution is fundamental for understanding the cellular ultrastructure. Whereas important insights into the architecture of microfilament networks have been gained by negative staining, critical point drying, and freeze-fracturing methods, it is cryoelectron tomography that provides, for the first time, a comp...

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Rheology of the Cytoskeleton

The cytoskeleton is the primary internal structure of the cell, providing its structural integrity. The rheology and mechanics of the cytoskeleton, therefore, are key to the cell’s ability to accomplish its diverse functions in health and disease. Although the importance of the cytoskeleton is well established, the relationship between the microstructural details and the macroscopic rheological...

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ژورنال

عنوان ژورنال: Kanzo

سال: 1999

ISSN: 0451-4203,1881-3593

DOI: 10.2957/kanzo.40.579